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In the eye, Sosne et al., Exp Eye Res 2001 reported accelerated corneal re-epithelialisation and reduced inflammation after injury, and in the central nervous system Xiong et al., J Neurosurg 2012 found that T4 initiated six hours after experimental traumatic brain injury improved sensorimotor and spatial-learning recovery while enhancing hippocampal neurogenesis

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A 2023 study found topical KPV reduced inflammatory cytokine expression in psoriatic plaques by 63% within four weeks

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Mitochondrial dysfunction is increasingly recognized as a contributor to neuropathy, particularly in diabetic and chemotherapy-induced forms where mitochondrial damage in dorsal root ganglion neurons precedes and contributes to axonal degeneration